Since its founding in 2010 as an art fair that works very hard not to look or feel like an art fair, Independent has prospered in its home in the funky old building on West 22nd Street that once housed the Dia Center for the Arts, whose rough brick walls practically breathe downtown art history.

But the fit wasn’t perfect. The elevators were tiny; climbing the narrow, winding staircase could feel like scaling the Matterhorn in the middle of an avalanche; and the building’s future was never certain. Last year, it was sold (it will be torn down for high-end condos), and Independent’s co-founder, the gallery owner Elizabeth Dee, said she spent several anxious months looking for — and not finding — Manhattan space to suit the fair. But it has now found a home in an unconventional kind of setting: Spring Studios in TriBeCa, the New York outpost of a fashion-focused company that has run a sprawling studio and exhibition space in North London for almost 20 years.